Anish K. Simhal, PhD
Postdoctoral Fellow, Autism Center
Child Mind Institute
Anish K. Simhal, PhD, is a postdoctoral fellow in the Autism Center at the Child Mind Institute. His research includes examining changes in the connectome caused by autism spectrum disorders and analyzing fMRI and dMRI images.
Anish earned his PhD in Electrical Engineering from Duke University in Dr. Guillermo Sapiro’s lab. At Duke, his graduate work focused on developing and validating a suite of computational tools for neuroscientists. These included a probabilistic synapse detection method for detecting synapses in array tomography data (an imaging method for ultrathin slices of brain tissue labeled with antibodies) without training data, a synaptic antibody characterization tool for validating antibody performance on array tomography data, and applying these tools to better understand the relationship between astrocytes and synapses in a mouse model of fragile X syndrome. Anish has also worked with the Duke Center for Autism and Brain Development to analyze the efficacy of using curvature, a graph theory measure, to evaluate changes in connectivity imaged via diffusion tensor imaging.