Persistent Depressive Disorder Basics


PDD: Treatment

Treatments for persistent depressive disorder include medications and psychotherapy, including cognitive behavioral therapy and interpersonal therapy. Medications are believed to be a more effective treatment than psychotherapy when used alone, but a combination of medication and psychotherapy is believed to be the most effective treatment. Medications include selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs) and tricyclic antidepressants (TCAs). Children and young adults should be closely monitored by their health-care providers and their families when taking antidepressants, especially when they have just begun taking them or when their dose has recently been changed.