Amy Margolis, PhD

Dr. Amy Margolis is a professor of psychiatry and behavioral health at The Ohio State University and director of the Environment, Brain, and Behavior Lab as well as the Psychology, Psychiatry, and Public Health Collaborative Learning Disability Innovation Hub funded by the National Institute of Child Health and Human Development. She holds a doctorate in Applied Educational Psychology: School Psychology from Teachers College, Columbia University, and is trained as a clinical neuropsychologist with two decades of experience assessing and treating children with learning and attention disorders.

Dr. Margolis is the principal investigator on a number of federally funded projects that use neuroimaging (magnetic resonance imaging [MRI] and electroencephalography [EEG]) in longitudinal birth cohorts to study the effects of prenatal exposure to neurotoxicants on brain and behavior outcomes. Her lab’s research focuses on identifying neural correlates of environmentally associated reading and math problems in children living in the context of economic disadvantage. In addition the lab studies environmentally associated phenotypes of attention, substance use, and thought problems.

In a complementary line of research, the lab studies how disruptions in visual-spatial processing and circuits underlying such capacities impair children’s functioning. Dr. Margolis has established the prevalence, etiology, pathophysiology, and treatment of nonverbal learning disability (NVLD), which was first described in the 1960s, and differentiates children with deficits in visual-spatial reasoning from those with language-based (verbal) learning problems. She published the first population estimate of NVLD, placing rates at 3 percent in North American youth, and the first functional MRI studies of NVLD, linking brain alterations with functional impairments in youth with NVLD. She is project lead, along with Dr. Prudence Fisher, in reconceptualizing NVLD as developmental visual-spatial disorder (DVSD) and developing a submission to the DSM5TR for consideration of the disorder in the manual. Her work has also shown that prenatal exposure to air pollution and social stress are associated with reduced hippocampal volumes and visual-spatial processing, pointing to a possible etiologic pathway of DVSD/NVLD.

Dr. Margolis is the author of two books on learning disorders and DVSD/NVLD and over 80 peer-reviewed papers. She has served as the text reviser for the chapter on specific learning disorder for DSM 5TR  and as co-chair of the ECHO (Environmental Influences on Children’s Health Outcomes) Neurodevelopment Working Group. 

• PhD, Applied Educational Psychology, Teachers College, Columbia University
• BA, Biochemistry and Molecular Biology: The Evolution of Human Behavior, UC Berkeley