Arno Klein, PhD

Director of Innovative Technologies; Joseph Healey Scholar; Research Scientist, Center for the Developing Brain

Child Mind Institute

Arno Klein, PhD

Arno Klein is the Child Mind Institute’s Director of Innovative Technologies, Joseph Healey Scholar, and Research Scientist in the Center for the Developing Brain. He is developing a Sensors and Wearables Program to study mental illness and offer potential interventions.

Dr. Klein builds upon recent experience as the scientific lead on the mPower Parkinson mobile health research study launched last year by Apple. The mPower study is an example of how mobile devices can vastly scale up open medical research, in this case by tracking symptoms of Parkinson disease from iPhone sensors in thousands of participants. Dr. Klein created an open source software pipeline for analyzing sensor data and designed interactive visualizations to present results to patients, clinicians and researchers.

This mobile health research work exemplifies Dr. Klein’s passionate adherence to open science, where researchers share data, code, resources and ideas, and where collective, collaborative endeavors are preferred over separate silos of independent research. At Sage Bionetworks, he spearheaded several open science initiatives, and helped to coordinate open biomedical challenges such as the Alzheimer’s Disease Big Data DREAM Challenge.

Dr. Klein also develops open source software for brain image analysis. He oversaw the construction of a new brain labeling protocol and the world’s largest manually labeled set of brain images, labeled according to this more consistent and accurate protocol. He created and continues to be the main developer of the open source Mindboggle software for automated brain feature extraction, labeling and shape analysis. Using the Mindboggle software, he recently completed the largest brain shape study ever conducted, and has published some of the largest brain image analysis evaluation studies ever performed.

See Dr. Klein’s personal website for publications and descriptions of ongoing projects, including those on brain imaging, visual taxonomies and cave temple photography.

Experience

  • Director of Neuroimaging, Principal Scientist of Systems Biology, Sage Bionetworks, Seattle, WA (2014-2016)
  • Research Assistant Professor, Department of Psychiatry and Behavioral Science, State University of New York (SUNY) at Stony Brook (2012-2013)
  • Assistant Professor of Clinical Neurobiology, Division of Molecular Imaging and Neuropathology, Department of Psychiatry, New York State Psychiatric Institute, Columbia University (2007-2012)
  • Information Synthesis Theorist and Program Analyst, Parsons Institute for Information Mapping, The New School, NY (2004-2007)

Education

  • PhD, Neuroscience, Weill Medical College, Cornell University, NY
    Functional MRI Laboratory, Memorial Sloan-Kettering Cancer Center
    Functional MRI Research Center, Columbia University
  • Computation and Neural Systems Program, California Institute of Technology
  • MS, Media Arts and Sciences, Spatial Imaging Group, MIT Media Laboratory, Massachusetts Institute of Technology
  • BS, Biopsychology, Perception and Cognition Studies, University of Michigan (Ann Arbor)