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Arno Klein, PhD

Arno Klein, PhD

Director of Innovative Technologies; Joseph Healey Scholar; Senior Research Scientist, Center for the Developing Brain
Child Mind Institute

Arno Klein, PhD, joined the Child Mind Institute in 2016 as the director of innovative technologies. He prototypes and directs the development of mind-assisting technologies for therapy, education, and research, which you can learn more about on his personal website.

At the Child Mind Institute, Dr. Klein has spearheaded a variety of projects, including MindLogger, Mosaic, and LinguaLearn. MindLogger is a no-code-configurable, end-to-end encrypted, mobile data collection and administration platform. Its goal is to make mental health assessment, therapy, and research more accessible, personalized, transparent, and trustworthy. Mosaic is a database under active development that will return personalized mental health guides and other recommended resources for client applications such as MindLogger. LinguaLearn comprises a set of speech and language training tools that are under active development. Dr. Klein’s MATTER Lab has also created a variety of wearable devices such as Helios, a wrist-worn position tracker that monitors compulsive behaviors (such as hair pulling and nail biting) and can provide alerts by haptic feedback on the wrist.

Dr. Klein previously worked at Sage Bionetworks, where he was the scientific lead on the mPower study, an iPhone-based research study of Parkinson’s Disease launched by Apple with over 10,000 participants. He also created an open-source software pipeline for analyzing sensor data, designed interactive visualizations to present results to patients, clinicians, and researchers, and helped to coordinate open biomedical challenges such as the Alzheimer’s Disease Big Data DREAM Challenge.

In his positions at both Columbia University and Stony Brook University, Dr. Klein developed open-source software for brain image analysis and conducted research on imaging biomarkers of depression and PTSD. He oversaw the construction of a new human brain labeling protocol and the world’s largest manually labeled set of human brain images. Additionally, he created the Mindboggle software and used it to run the largest brain shape study ever conducted.

Dr. Klein has also worked with the Parsons Institute for Information Mapping, where he designed data visualization and information visualization tools, inventing a visualization taxonomy as a formalism for deconstructing and classifying images by their visual composition.

Dr. Klein is a champion of open science and believes in the power of technology to deliver mental health care to all who need it.


  • Director of Neuroimaging and Principal Scientist of Systems Biology, Sage Bionetworks
  • Research Assistant Professor, Department of Psychiatry and Behavioral Science, Stony Brook University
  • Assistant Professor of Clinical Neurobiology, Columbia University
  • Information Synthesis Theorist and Program Analyst, Parsons Institute for Information Mapping


  • PhD, Neuroscience, Weill Medical College, Cornell University, NY
  • Functional MRI Laboratory, Memorial Sloan-Kettering Cancer Center
  • Functional MRI Research Center, Columbia University
  • Computation and Neural Systems Program, California Institute of Technology
  • MS, Media Arts and Sciences, Spatial Imaging Group, MIT Media Laboratory, Massachusetts Institute of Technology
  • Perception and Cognition Studies, University of Michigan (Ann Arbor)