Ketamine and Glutamate Modulators for Difficult-to-Treat Depression: Challenges and Opportunities
Sanjay J. Mathew, MD, is the Marjorie Bintliff Johnson and Raleigh White Johnson Jr. vice chair for research and a professor in the Menninger Department of Psychiatry and Behavioral Sciences at Baylor College of Medicine.
About This Event
This lecture will provide an overview of ketamine and esketamine nasal spray for the treatment of medication-resistant depression, providing a summary of the evidence base for its efficacy as well as its risks. Key challenges for these approaches will be discussed, including how to prolong and extend transient benefit and identifying clinical and biological predictors of response. Finally, a recent large comparative effectiveness trial comparing ketamine with electroconvulsive therapy for treatment-resistant depression will be reviewed.
- Review the rationale and major findings supporting the use of rapid-acting NMDA antagonists (ketamine/esketamine) for adults with treatment-resistant depression
- Recognize the potential risks and adverse effects associated with this class of medications
- Discuss key challenges and opportunities for continued progress
About the Visiting Professor Lecture Series
The Child Mind Institute Visiting Professor Lecture Series invites leaders in the field of child and adolescent mental health to talk about the latest research and treatment protocols. All events are open to the public. This year, all lectures will be hosted virtually over Zoom. In partnership with Northwell Health, continuing medical education (CME) credits for psychiatrists and continuing education (CE) credits for psychologists are available to registered course participants.