Low DM, Mair P, Nock MK, Ghosh SS (2025)
Advancing Methods
AI, Risk, and Contemplative Science (ARC) Lab
Using data science to analyze people’s speech and language across the arc of mental health, from psychological risk to contemplative flourishing.
About Our Work
The ARC Lab develops technology for scalable and equitable access to mental health assessments and interventions — combining methods from natural language processing, large language models (LLMs), speech processing, machine learning, psychometrics, and causal inference.
We focus on analyzing diverse phenomenological natural language and speech data, including clinical interviews, social media posts, journal entries, and chatbot conversations.
Risk Research
We develop psychometrically rigorous methods for assessing mental health from text data. Our research has identified which symptoms indicate the highest risk of suicide from crisis hotline conversations and social media posts, and we created an open-source toolbox to measure symptoms in text using LLMs.
We examine how voice changes across mental health conditions. Our work focuses on detecting speech changes that occur as individuals become suicidal, with the goal of improving risk assessments.
We study how to regulate and evaluate AI chatbots when users are suicidal. Our current work explores whether users are able to recognize when suicidal and delusional concerns should be challenged rather than validated during AI chatbot interactions.
Selected Risk Research Papers
Low DM, Rankin O, Bentley KH, Nock MK Ghosh SS (2026)
Khazanov G*, Franz PJ*, Stade EC, Kelly D, Poerio MJ, Maitlin C, Emery K, Low DM, …, Wiltsey Stirman S (2026)
Low DM, Rumker, L, Talkar T, Torous J, Cecchi G, Ghosh SS (2020)
Damiano RF, Low DM, Ito LT, Santoro ML, Belangero S, Pan PM, Casella C, Schäfer JL, Blumberg HP, Miguel EC, Rohde LAP, Salum GA (2026)
Contemplative Science
The Child Mind Institute’s Mirror journaling app, which serves as a privacy-preserving phenotyping tool to assess suicide risk, circadian rhythms, energy, arousal, and mood, has been shown to reduce anxiety. Our ongoing research explores the similarities and differences between meditation and journaling.
Mindfulness and other psychological factors help explain changes in mental health following naturalistic psychedelic use. We are currently testing whether mindfulness meditation can reduce stress in low-income populations. We are also exploring the emergence of insight and its effects after psychedelic use.
Chatbot users often turn to AI for support with existential and spiritual concerns related to meaning, purpose, and death. We are investigating the potential and limits of AI in providing guidance in these domains.
Selected Contemplative Science Papers
Milham MP, Low DM, Erkent A, Trabulsi J, Kass M, Vos de Wael R, Yenepalli S, Wang Y, Leyden M, Jordan C, Salum GA, Alexander L, Schubiner G, Hendrix L, Koyama MS, Mears L, McAdam R, White C, Merikangas K, Satterthwaite TD, Franco AR, Klein A, Koplewicz H, Leventhal B, Freund M, Kiar G (2026)
Kim M, Low DM, Lafond D, Shim C, Han M, Kandil M, Zhang C, Kitsberg T, Boccagno C, Liang PP, Maes P (2026)
Herrmann FH*, Jones G*, Low DM, Carhart-Harris R, Kettner H (2025)
Collaborate With Us
If you are interested in exploring a collaboration or volunteer internship, please fill out our inquiry form. You can also explore our current network of collaborators.
Our Team