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AI, Risk, and Contemplative Science (ARC) Lab

Advancing Methods

AI, Risk, and Contemplative Science (ARC) Lab

Using data science to analyze people’s speech and language across the arc of mental health, from psychological risk to contemplative flourishing.

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About Our Work

The ARC Lab develops technology for scalable and equitable access to mental health assessments and interventions — combining methods from natural language processing, large language models (LLMs), speech processing, machine learning, psychometrics, and causal inference.

We focus on analyzing diverse phenomenological natural language and speech data, including clinical interviews, social media posts, journal entries, and chatbot conversations.

Our Application Areas

Identifying

Identifying Risk

We study suicide risk, the impact of social media on mental health, and the risk of AI chatbots when used for psychological support.

Contemplative

Contemplative Science

We study how heightened states of acceptance, insight, and compassion can move people from risk to flourishing.

Risk Research

Text Psychometrics

We develop psychometrically rigorous methods for assessing mental health from text data. Our research has identified which symptoms indicate the highest risk of suicide from crisis hotline conversations and social media posts, and we created an open-source toolbox to measure symptoms in text using LLMs.

Voice and Speech Biomarkers

We examine how voice changes across mental health conditions. Our work focuses on detecting speech changes that occur as individuals become suicidal, with the goal of improving risk assessments.

The Risk of AI Chatbots for Mental Health

We study how to regulate and evaluate AI chatbots when users are suicidal. Our current work explores whether users are able to recognize when suicidal and delusional concerns should be challenged rather than validated during AI chatbot interactions.

Selected Risk Research Papers

Selected Risk Research Papers

Text psychometrics: Assessing psychological constructs in text using natural language processing

Low DM, Mair P, Nock MK, Ghosh SS (2025)

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Using large language models to create lexicons for interpretable text models with high content validity: The Suicide Risk Lexicon

Low DM, Rankin O, Bentley KH, Nock MK Ghosh SS (2026)

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Development of a consensus statement to guide AI chatbot responses to suicide risk disclosure

Khazanov G*, Franz PJ*, Stade EC, Kelly D, Poerio MJ, Maitlin C, Emery K, Low DM, …, Wiltsey Stirman S (2026)

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Natural language processing reveals vulnerable mental health support groups and heightened health anxiety on Reddit during COVID-19: Observational study

Low DM, Rumker, L, Talkar T, Torous J, Cecchi G, Ghosh SS (2020)

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Developmental predictors of suicide attempts from childhood to early adulthood: A 15-year prospective cohort study of incidence, age of onset, and number of attempts

Damiano RF, Low DM, Ito LT, Santoro ML, Belangero S, Pan PM, Casella C, Schäfer JL, Blumberg HP, Miguel EC, Rohde LAP, Salum GA (2026)

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Contemplative Science

Journaling

The Child Mind Institute’s Mirror journaling app, which serves as a privacy-preserving phenotyping tool to assess suicide risk, circadian rhythms, energy, arousal, and mood, has been shown to reduce anxiety. Our ongoing research explores the similarities and differences between meditation and journaling.

Psychedelics, Mindfulness, and Insight

Mindfulness and other psychological factors help explain changes in mental health following naturalistic psychedelic use. We are currently testing whether mindfulness meditation can reduce stress in low-income populations. We are also exploring the emergence of insight and its effects after psychedelic use.

Limits of AI for Existential Concerns

Chatbot users often turn to AI for support with existential and spiritual concerns related to meaning, purpose, and death. We are investigating the potential and limits of AI in providing guidance in these domains.

Selected Contemplative Science Papers

Selected Contemplative Science Papers

Digital journaling enables privacy-preserving behavioral phenotyping and real-time risk monitoring at scale

Milham MP, Low DM, Erkent A, Trabulsi J, Kass M, Vos de Wael R, Yenepalli S, Wang Y, Leyden M, Jordan C, Salum GA, Alexander L, Schubiner G, Hendrix L, Koyama MS, Mears L, McAdam R, White C, Merikangas K, Satterthwaite TD, Franco AR, Klein A, Koplewicz H, Leventhal B, Freund M, Kiar G (2026)

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Breaking the negative cycle: A self-reflection system for adaptive change

Kim M, Low DM, Lafond D, Shim C, Han M, Kandil M, Zhang C, Kitsberg T, Boccagno C, Liang PP, Maes P (2026)

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Exploring the potential psychological predictors associated with changes in depression, anxiety, and well-being following naturalistic psychedelic use

Herrmann FH*, Jones G*, Low DM, Carhart-Harris R, Kettner H (2025)

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Collaborate With Us

Collaborate With Us

If you are interested in exploring a collaboration or volunteer internship, please fill out our inquiry form. You can also explore our current network of collaborators.

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