Please upgrade to Microsoft Edge, Google Chrome, or Firefox.
Lo sentimos, la página que usted busca no se ha podido encontrar. Puede intentar su búsqueda de nuevo o visitar la lista de temas populares.
Conor Liston, MD, PhD, is a clinical psychiatrist specializing in the management of treatment-resistant mood disorders. He’s also an associate professor of neuroscience and psychiatry at Weill Cornell Medicine.
Depression is a heterogeneous psychiatric disorder, not a unitary disease entity. It is assumed to comprise multiple subtypes that are driven by different pathophysiological mechanisms and require different treatments, but there is no consensus on how to treat them. Here, I will discuss recent progress in parsing heterogeneity in depression by defining subtypes anchored in fMRI measures of functional connectivity and other biological features. Next, I will discuss new findings from longitudinal imaging studies of densely sampled individuals, showing that the frontostriatal salience network is expanded twofold in most individuals with depression. These findings demonstrate that salience network expansion was unexpectedly stable over time, unaffected by changes in mood state, detectable in children before the subsequent onset of depressive symptoms in adolescence, and caused primarily by network border shifts affecting specific functional systems, with three distinct modes of encroachment occurring in different individuals. I will conclude by reviewing new methods for antidepressant treatment matching based on these approaches.
The Child Mind Institute Visiting Professor Lecture Series invites leaders in the field of child and adolescent mental health to talk about the latest research and treatment protocols. All events are open to the public. This year, all lectures will be hosted virtually over Zoom. In partnership with Northwell Health, continuing medical education (CME) credits for psychiatrists and continuing education (CE) credits for psychologists are available to registered course participants.
"*" indicates required fields
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
To kick off Autism Awareness and Acceptance Month, will you help us reach 100 donors by midnight on Friday, 4/4?
Get updates on our care services in California and resources to support children’s mental health.
"*" indicates required fields
Get exclusive updates on our care services and resources to support children’s mental health.
"*" indicates required fields
Notifications