An increasing number of children with emotional or behavioral problems are being treated with more than one medication, a practice called polypharmacy. This guide outlines what parents should know in order to make informed decisions about your child’s medication, especially when more than one is involved.
Making decisions about medication for a child with emotional or behavioral problems can be daunting, especially when more than one medication is involved.
When children have complex psychiatric symptoms, or aren’t responding adequately to a medication they are taking, doctors often recommend adding another medication.
Taking multiple psychoactive medications is called “polypharmacy.” And studies show that the number of children taking more than one medication is soaring.
Combining medications can be effective when they’re prescribed and monitored carefully by a doctor who is an expert in using them with children. But it’s important for parents to be informed about the risks inherent in adding medications, and signs that you should be concerned about what a doctor is recommending.
These are the most common reasons why a doctor might recommend adding a medication:
There is very little scientific evidence about the safety and effectiveness of multiple medications in children. But clinical evidence suggests that medication “cocktails” can be safe and effective when prescribed by a doctor who is very well informed about the medications and has extensive experience treating children with them.
Experience with treating adults is not enough to guide treatment of children, because kids, whose nervous systems are still maturing, don’t always respond to medication the same way adults do.
But adding medications should not be done in lieu of behavioral treatments that have been shown to be effective for kids with many issues, including ADHD, anxiety, depression and disruptive behavior. The combination of a single medication and behavioral treatment should be carefully considered before adding more medication.
The risk in combining medications is that they may interact in a way that increases uncomfortable or harmful side effects. For instance, explains Dr. Ron Steingard, a child and adolescent psychiatrist at the Child Mind Institute, you can get overlapping side effects. If one medication causes mild sedation and the second does the same thing, the result can be so much sedation that the child isn’t herself and can’t stay awake.
Another type of interaction that can be problematic, Dr. Steingard adds, can occur if two medications use the same metabolic pathway — the mechanism in the body that breaks them down and delivers them to the target. If that pathway is overwhelmed, it can create a buildup of medication, causing the kind of side effects you’d see with a much higher dose of one of the meds.
If you are worried that your child is on too many different medications, or your child is not doing well on them, Dr. Steingard recommends that your first step should be to go to your prescribing doctor with your concerns. Tell your doctor that you’d like to get a second opinion. It’s your right, and it’s common in other areas of medicine. A good doctor will be supportive, and may be able to help you find another clinician to review your child’s case.
The children most at risk for taking multiple medications that could be harmful are those with disruptive or dangerous behavior.
When kids are unmanageable at home and at school, doctors generally try whatever pharmaceutical tools are available to help them. If one medication helps a little, but not enough, doctors may add more medications to try to get a better outcome. And another. And so on.
Dr. Steingard, who’s seen children on as many as a dozen meds, recommends exploring behavioral supports before using multiple medications.
If a child has a learning or attention disorder and is frustrated at school, she should have supports there. If she is out of control at home, parent training can be very helpful. Anxiety and depression, which might also be causing aggression, both respond well to behavioral treatments.
Thinking beyond medication is an important part of the solution to complex problems that’s often overlooked.
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